Closed Studies

Low-Dose Tamoxifen Breast Cancer Prevention Study


Dr. Melanie Palomares, City of Hope, Dr. Sofia Merajver, University of Michigan, Dr. Melissa Hudson, St. Jude Children’s Research Hospital, Dr. Ruth O’Regan, Emory University, Dr. David Hodgson, Princess Margaret Hospital

Study Review

This study at City of Hope in Duarte, Calif., is investigating the effect two years of low-dose tamoxifen has on breast density and other biological markers (biomarkers) associated with increased breast cancer risk in women who had been diagnosed and treated with chest or axilla radiation before the age of 40 for a cancer other than breast cancer. The study is also measuring the safety and tolerability of tamoxifen at the lower dose. The researchers wanted to enroll up to 230 volunteers from various cities around the US and reached out to the Army of Women (AOW) to supplement their other recruitment sources. The Call to Action for this study was sent to AOW members on May 2, 2012, and the researchers closed enrollment on March 19, 2015. The AOW provided them with 13 women who were interested in enrolling in the study.



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