Researcher

Sophocles Voineskos MD, McMaster University

Summary

The BREAST-Q is currently the gold standard patient-reported outcome measure (PROM) for measuring health-related quality of life in breast cancer. Recently, new BREAST-Q scales have been developed and validated to measure breast sensation outcomes. However, the minimally important differences (MID) of these measures have yet to be established, nor has normative data. This study is an online, cross-sectional questionnaire. Participants will be asked to complete six BREAST-Q domains, and demographic and clinical (e.g., type and timing of breast reconstruction) information. Group 1 (participants who underwent any type of post-mastectomy breast reconstruction between 12 and 60 months prior) will also complete transition rating anchor questions that ask about the change in their breast sensation compared to before their surgery, which will serve as the anchor for MID estimation.

A diminished or complete loss of sensation in transplanted tissue after autologous breast reconstruction can be detrimental to patients’ quality of life. As mentioned, new BREAST-Q scales have been developed and validated to measure breast sensation outcomes however the minimally important differences (MID) of these measures have yet to be established. The MID is the smallest change in the outcome of interest, either beneficial or harmful, that patients would perceive as important and it is the most commonly used reference point for PROM interpretation is the minimally important difference (MID). Establishing a MID allows for the interpretation of treatment effects between interventions compared in clinical trials and meta-analyses of clinical trials, giving decision-makers the ability to determine whether or not individual patients have achieved a patient-important benefit.

What does participation involve?
You must complete a survey.

Where?
Anywhere in the U.S. and virtual

How can I sign up for this study?

You can sign up for this study if you match all of these main criteria. Please read this list carefully.

  • You are a female (assigned at birth)
  • You are ≥18 years old
  • You must be able to read English
  • Participants will have undergone any type of post-mastectomy breast reconstruction between 12 and 60 months prior (Group 1), undergone any type of post-mastectomy breast reconstruction between 1 and 6 months prior (Group 2), or will be women who have not undergone any type of breast cancer related surgery (Group 3)

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We combat the disparities that exist in research by challenging the scientific community to launch studies that are as inclusive and diverse as the people that breast cancer affects.

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